Article
Microarray profiling of DNA extracted from FFPE tissues using SNP 6.0 Affymetrix platform.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Tuefferd Marianne, de Bondt An, Van den Wyngaert Ilse, Talloen Willem, Göhlmann Hinrich
Abstract excerpt
High-density oligonucleotide microarrays are commonly used for GWAS studies as well as for tumor genome alteration identifications. The recent Affymetrix Genome-Wide SNP 6.0 microarray generation has two major advantages: (1) showing high genome coverage and (2) starting with very small amount of DNA material. The hybridization protocol needs to be standardized and highly reproducible, as DNA is first digested by...
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