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Article

Whole genome amplification for array comparative genomic hybridization using DNA extracted from formalin-fixed, paraffin-embedded histological sections.

The Journal of molecular diagnostics : JMD - 1 Mar 2009

Huang Jian, Pang Jesse, Watanabe Takuya, Ng Ho-Keung, Ohgaki Hiroko

Abstract excerpt

Array comparative genomic hybridization (CGH) is useful to assess genome-wide chromosomal imbalance, but the requirement for relatively large amounts of DNA can be a limitation, in particular for samples extracted from small tumor areas on paraffin sections. Whole genome amplification (WGA) can be performed before array CGH to obtain sufficient DNA, but the possibility of artifacts attributable to biased...

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Identifiers

PMID: 19197000
DOI: 10.2353/jmoldx.2009.080143
PMCID: PMC2665860

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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