Article
Genome-wide copy number alterations detection in fresh frozen and matched FFPE samples using SNP 6.0 arrays.
Genes, chromosomes & cancer - 1 Nov 2008
Tuefferd Marianne, De Bondt An, Van Den Wyngaert Ilse, Talloen Willem, Verbeke Tobias, Carvalho Benilton, Clevert Djork-Arne, Alifano Marco, Raghavan Nandini, Amaratunga Dhammika, Göhlmann Hinrich, Broët Philippe, Camilleri-Broët Sophie
Abstract excerpt
SNP arrays offer the opportunity to get a genome-wide view on copy number alterations and are increasingly used in oncology. DNA from formalin-fixed paraffin-embedded material (FFPE) is partially degraded which limits the application of those technologies for retrospective studies. We present the use of Affymetrix GeneChip SNP6.0 for identification of copy number alterations in fresh frozen (FF) and matched FFPE...
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