Article
eCEO: an efficient Cloud Epistasis cOmputing model in genome-wide association study.
Bioinformatics (Oxford, England) - 15 Apr 2011
Wang Zhengkui, Wang Yue, Tan Kian-Lee, Wong Limsoon, Agrawal Divyakant
Abstract excerpt
MOTIVATION: Recent studies suggested that a combination of multiple single nucleotide polymorphisms (SNPs) could have more significant associations with a specific phenotype. However, to discover epistasis, the epistatic interactions of SNPs, in a large number of SNPs, is a computationally challenging task. We are, therefore, motivated to develop efficient and effective solutions for identifying epistatic...
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