Article
The complete compositional epistasis detection in genome-wide association studies.
BMC genetics - 19 Feb 2013
Wan Xiang, Yang Can, Yang Qiang, Zhao Hongyu, Yu Weichuan
Abstract excerpt
BACKGROUND: The detection of epistasis among genetic markers is of great interest in genome-wide association studies (GWAS). In recent years, much research has been devoted to find disease-associated epistasis in GWAS. However, due to the high computational cost involved, most methods focus on specific epistasis models, making the potential loss of power when the underlying epistasis models are not examined in...
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