Article
Parallelizing Epistasis Detection in GWAS on FPGA and GPU-Accelerated Computing Systems.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
González-Domínguez Jorge, Wienbrandt Lars, Kässens Jan Christian, Ellinghaus David, Schimmler Manfred, Schmidt Bertil
Abstract excerpt
High-throughput genotyping technologies (such as SNP-arrays) allow the rapid collection of up to a few million genetic markers of an individual. Detecting epistasis (based on 2-SNP interactions) in Genome-Wide Association Studies is an important but time consuming operation since statistical computations have to be performed for each pair of measured markers. Computational methods to detect epistasis therefore...
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