Article
EpiMC: Detecting Epistatic Interactions Using Multiple Clusterings.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Wang Jun, Zhang Huiling, Ren Wei, Guo Maozu, Yu Guoxian
Abstract excerpt
Detecting single nucleotide polymorphisms (SNPs) interactions is crucial to identify susceptibility genes associated with complex human diseases in genome-wide association studies. Clustering-based approaches are widely used in reducing search space and exploring potential relationships between SNPs in epistasis analysis. However, these approaches all only use a single measure to filter out nonsignificant SNP...
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