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Article

COE: a general approach for efficient genome-wide two-locus epistasis test in disease association study.

Journal of computational biology : a journal of computational molecular cell biology - 1 Mar 2010

Zhang Xiang, Pan Feng, Xie Yuying, Zou Fei, Wang Wei

Abstract excerpt

The availability of high-density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Two-locus epistasis (gene-gene interaction) detection has attracted great research interest as a promising method for genetic analysis of complex diseases. In this article, we propose a general approach, COE, for efficient large scale gene-gene interaction analysis,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20377453
DOI: 10.1089/cmb.2009.0155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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