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Article

Methylation profiling of rectal cancer identifies novel markers of early-stage disease

24 Feb 2011

Abstract excerpt

BACKGROUND: Radical surgery is the de facto treatment for early rectal cancer. Conservative surgery with transanal endoscopic microsurgery can achieve high rates of cure but the histopathological measures of outcome used to select local treatment lack precision. Biomarkers associated with disease progression, particularly mesorectal nodal metastasis, are urgently required. The aim was to compare patterns of...

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PMID: 21360524
DOI: 10.1002/bjs.7422

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