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Article

Gene methylation in rectal cancer: Predictive marker of response to chemoradiotherapy?

23 May 2013

Abstract excerpt

Although numerous studies have focused on the link between CpG island methylator phenotypes and the development of colorectal cancer, few studies have dealt specifically with methylation profiling in rectal cancer and its role in predicting response to neoadjuvant chemoradiotherapy (NCRT). We characterized methylation profiles in normal and neoplastic tissue samples from patients with rectal cancer and assessed...

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Share to Colorectal Cancer Screening and Detection
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PMID: 23702823
DOI: 10.1002/jcp.24405

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