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Article

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

16 Feb 2011

Abstract excerpt

BACKGROUND: Androgen receptor (AR) controls male morphogenesis, gametogenesis and prostate growth as well as development of prostate cancer. These findings support a role for AR in cell migration and invasiveness. However, the molecular mechanism involved in AR-mediated cell migration still remains elusive. METHODOLOGY/PRINCIPAL FINDINGS: Mouse embryo NIH3T3 fibroblasts and highly metastatic human fibrosarcoma...

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Identifiers

PMID: 21359179
DOI: 10.1371/journal.pone.0017218

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Related research

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Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A AssociationPMID 21359179Read ↗

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Androgen Receptor Nuclear Translocation Is Facilitated by the f-Actin Cross-Linking Protein FilaminSemantic proximity Read ↗

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FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration.Semantic proximity Read ↗

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