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Article

Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells.

Journal of cell science - 15 Aug 2012

Baldassarre Massimiliano, Razinia Ziba, Brahme Nina N, Buccione Roberto, Calderwood David A

Abstract excerpt

Filamins are an important family of actin-binding proteins that, in addition to bundling actin filaments, link cell surface adhesion proteins, signaling receptors and channels to the actin cytoskeleton, and serve as scaffolds for an array of intracellular signaling proteins. Filamins are known to regulate the actin cytoskeleton, act as mechanosensors that modulate tissue responses to matrix density, control cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22595522
DOI: 10.1242/jcs.104018
PMCID: PMC3462082

Genes

MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells.PMID 22595522Read ↗

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