Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells.

Cells - 22 Dec 2021

Di Donato Marzia, Giovannelli Pia, Barone Maria Vittoria, Auricchio Ferdinando, Castoria Gabriella, Migliaccio Antimo

Abstract excerpt

Prostate cancer (PC) is one of the most widespread malignancies among males worldwide. The androgen receptor (AR) plays a major role in prostate cancer development and progression and is the main target of PC therapy. Nonetheless, its action is not yet fully elucidated. We report here that the AR associates with Filamin A (FlnA) promoting migration and invasiveness of various PC-derived cells after androgen...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to Filamins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Focal Adhesion Protein-Tyrosine Kinases

Share to Neoplasm Invasiveness

Share to Prostatic Neoplasms

Share to rac1 GTP-Binding Protein

Share to Receptors, Androgen

Share to Spheroids, Cellular

Source

Open in PubMed Open full text

Identifiers

PMID: 35011576
DOI: 10.3390/cells11010014
PMCID: PMC8750472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells.PMID 35011576Read ↗

Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions.Semantic proximity Read ↗

Extranuclear partners of androgen receptor: at the crossroads of proliferation, migration, and neuritogenesisSemantic proximity Read ↗

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A AssociationSemantic proximity Read ↗

Role of actin-binding proteins in prostate cancerSemantic proximity Read ↗

Nuclear versus Cytoplasmic Localization of Filamin A in Prostate Cancer: Immunohistochemical Correlation with MetastasesSemantic proximity Read ↗

Role of non-genomic androgen signalling in suppressing proliferation of fibroblasts and fibrosarcoma cellsSemantic proximity Read ↗

Analyzing the Androgen Receptor Interactome in Prostate Cancer: Implications for Therapeutic InterventionSemantic proximity Read ↗

Regulation of the Transcriptional Coactivator FHL2 Licenses Activation of the Androgen Receptor in Castrate-Resistant Prostate CancerSemantic proximity Read ↗

PROTACing the androgen receptor and other emerging therapeutics in prostate cancer.Semantic proximity Read ↗

Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer.Semantic proximity Read ↗

Unraveling the YAP1-TGFβ1 axis: a key driver of androgen receptor loss in prostate cancer-associated fibroblastsSemantic proximity Read ↗

Androgen Receptor Nuclear Translocation Is Facilitated by the f-Actin Cross-Linking Protein FilaminSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.