Article
Albuminuria and glomerular damage in mice lacking the metabotropic glutamate receptor 1.
The American journal of pathology - 1 Mar 2011
Puliti Aldamaria, Rossi Pia Irene Anna, Caridi Gianluca, Corbelli Alessandro, Ikehata Masami, Armelloni Silvia, Li Min, Zennaro Cristina, Conti Valerio, Vaccari Carlotta Maria, Cassanello Michela, Calevo Maria Grazia, Emionite Laura, Ravazzolo Roberto, Rastaldi Maria Pia
Abstract excerpt
The metabotropic glutamate (mGlu) receptor 1 (GRM1) has been shown to play an important role in neuronal cells by triggering, through calcium release from intracellular stores, various signaling pathways that finally modulate neuron excitability, synaptic plasticity, and mechanisms of feedback regulation of neurotransmitter release. Herein, we show that Grm1 is expressed in glomerular podocytes and that a...
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