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Article

Glcci1 Deficiency Leads to Proteinuria

24 Sept 2011

Abstract excerpt

Unbiased transcriptome profiling and functional genomics approaches identified glucocorticoid-induced transcript 1 (GLCCI1) as being a transcript highly specific for the glomerulus, but its role in glomerular development and disease is unknown. Here, we report that mouse glomeruli express far greater amounts of Glcci1 protein compared with the rest of the kidney. RT-PCR and Western blotting demonstrated that...

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PMID: 21949092
DOI: 10.1681/asn.2010111147

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