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Article

MSUT2 is a determinant of susceptibility to tau neurotoxicity.

Human molecular genetics - 15 May 2011

Guthrie Chris R, Greenup Lynne, Leverenz James B, Kraemer Brian C

Abstract excerpt

Lesions containing abnormal aggregated tau protein are one of the diagnostic hallmarks of Alzheimer's disease (AD) and related tauopathy disorders. How aggregated tau leads to dementia remains enigmatic, although neuronal dysfunction and loss clearly contribute. We previously identified sut-2 as a gene required for tau neurotoxicity in a transgenic Caenorhabditis elegans model of tauopathy. Here, we further...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21355046
DOI: 10.1093/hmg/ddr079
PMCID: PMC3080609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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