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Dynamics of the Cag-type IV secretion system ofHelicobacter pylorias studied by bacterial co-infections

11 Jul 2013

Abstract excerpt

Many pathogenic Gram-negative bacteria possess type IV secretion systems (T4SS) to inject effector proteins directly into host cells to modulate cellular processes to their benefit. The human bacterial pathogen Helicobacter pylori, a major aetiological agent in the development of chronic gastritis, duodenal ulcer and gastric carcinoma, harbours the cag-T4SS to inject the cytotoxin associated Antigen (CagA) into...

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PMID: 23844976
DOI: 10.1111/cmi.12166

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