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The Helicobacter pylori cag pathogenicity island as a determinant of gastric cancer risk

23 Feb 2024

Abstract excerpt

Helicobacter pylori strains can be broadly classified into two groups based on whether they contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI). Colonization of the human stomach with cag PAI-positive strains is associated with an increased risk of gastric cancer and peptic ulcer disease, compared to colonization with cag PAI-negative strains. The cag PAI encodes a secreted...

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PMID: 38391242
DOI: 10.1080/19490976.2024.2314201

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