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Assembly and molecular mode of action of the Helicobacter pylori Cag type IV secretion apparatus

1 Feb 2011

Abstract excerpt

Bacterial type IV secretion systems (T4SS) form supramolecular protein complexes that are capable of transporting DNA or protein substrates across the bacterial cell envelope and, in many cases, also across eukaryotic target cell membranes. Because of these characteristics, they are often used by pathogenic bacteria for the injection of host cell-modulating virulence factors. One example is the human pathogen...

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PMID: 21352490
DOI: 10.1111/j.1742-4658.2011.08036.x

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