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Article

Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori

1 Jan 2011

Abstract excerpt

Helicobacter pylori is a highly successful pathogen uniquely adapted to colonize humans. Gastric infections with this bacterium can induce pathology ranging from chronic gastritis and peptic ulcers to gastric cancer. More virulent H. pylori isolates harbour numerous well-known adhesins (BabA/B, SabA, AlpA/B, OipA and HopZ) and the cag (cytotoxin-associated genes) pathogenicity island encoding a type IV secretion...

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PMID: 22044679
DOI: 10.1186/1478-811x-9-28

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