Article
Multiple independent variants in 6q21-22 associated with susceptibility to celiac disease in the Dutch, Finnish and Hungarian populations.
European journal of human genetics : EJHG - 1 Jun 2011
Einarsdottir Elisabet, Bevova Marianna R, Zhernakova Alexandra, Monsuur Alienke, Koskinen Lotta L E, van't Slot Ruben, Mulder Chris, Mearin M Luisa, Korponay-Szabo Ilma R, Kaukinen Katri, Kurppa Kalle, Kere Juha, Mäki Markku, Wijmenga Cisca, Saavalainen Päivi
Abstract excerpt
Celiac disease is an inflammatory enteropathy caused by intolerance to gluten. Previous linkage studies in the Dutch, Finnish and Hungarian populations have revealed a locus on chromosome 6q21-22 conferring susceptibility to celiac disease. This locus has previously been implicated in susceptibility to other autoimmune diseases such as Crohn's disease and type 1 diabetes. We performed fine mapping on 446...
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