Article
5-HT2A receptor gene polymorphisms and irritable bowel syndrome.
Journal of clinical gastroenterology - 1 Jul 2011
Markoutsaki Theofano, Karantanos Theodoros, Gazouli Maria, Anagnou Nicholas P, Karamanolis Dimitrios G
Abstract excerpt
GOALS: The aim of the study was to investigate the potential association between single nucleotide polymorphisms of the 5-HT2A receptor gene and susceptibility to irritable bowel syndrome (IBS) in the Greek population. BACKGROUND: Serotonin [5-hydroxytryptamine (5-HT)] is the main mediator involved in the pathophysiology of IBS. Thus, genes implicated in 5-HT metabolism are good candidates for susceptibility to...
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