Article
Serotonin transporter gene polymorphisms in Southwestern Iranian patients with irritable bowel syndrome.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Jun 2013
Farjadian Shirin, Fakhraei Bahareh, Moeini Maryam, Nasiri Mahboubeh, Fattahi Mohammad Reza
Abstract excerpt
BACKGROUND AND STUDY AIMS: Irritable bowel syndrome is a common chronic functional gastrointestinal disorder of unknown etiology. Serotonin is an important factor in sensory signaling in the brain-gut axis, which plays a key role in intestinal motility and secretion. Serotonin clearance is mediated by a specific protein called the serotonin reuptake transporter. Transcription activity of the serotonin transporter...
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