Article
Association of the -1438 G/A and 102 T/C polymorphism of the 5-Ht2A receptor gene with irritable bowel syndrome 5-Ht2A gene polymorphism in irritable bowel syndrome.
Journal of clinical gastroenterology - 1 Aug 2004
Pata Cengiz, Erdal Emin, Yazc Kemal, Camdeviren Handan, Ozkaya Mahmut, Ulu Oguz
Abstract excerpt
GOALS: The aim of this study is to investigate whether there were any association between the 102 T/C and -1438 G/A polymorphisms of the 5-HT2A receptor gene and IBS, and abdominal pain, anxiety and depression. BACKGROUND: Genes involved in serotonin (5-HT) metabolism are good candidates for the pathogenesis of irritable bowel syndrome (IBS). Recently, a silent polymorphism in the 5-HT2A receptor gene was...
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