Article
Association study of serotonin 2A receptor (5-HT2A) and serotonin transporter (5-HTT) gene polymorphisms with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Apr 2007
Sáiz Pilar A, García-Portilla M Paz, Arango Celso, Morales Blanca, Alvarez Victoria, Coto Eliécer, Fernández Juan M, Bascarán M Teresa, Bousoño Manuel, Bobes Julio
Abstract excerpt
OBJECTIVE: To investigate (i) the association between four serotonergic polymorphisms (A-1438G and T102C of the 5-HT2A receptor gene, and 5-HTT VNTR and 5-HTTLPR of the 5-HT transporter gene) and schizophrenia and (ii) the potential interaction of those polymorphisms in the development of schizophrenia. SUBJECTS AND METHODS: 227 outpatients with schizophrenia (DSM-IV criteria) and 420 unrelated healthy controls...
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