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Article

The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies.

BMC gastroenterology - 10 Feb 2014

Zhang Zhi-Feng, Duan Zhi-Jun, Wang Li-Xia, Yang Dong, Zhao Gang, Zhang Lin

Abstract excerpt

BACKGROUND: The results of previous studies assessing the association between the 5-HTTLPR polymorphism of serotonin transporter gene and irritable bowel syndrome (IBS) are inconsistent. The aim of this study was to clarify the association between the 5-HTTLPR mutation and the presence of IBS and its subtypes with a meta-analysis of 25 studies. METHODS: A thorough search for case-control studies evaluating the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24512255
DOI: 10.1186/1471-230X-14-23
PMCID: PMC3926682

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