Article
Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.
Journal of virology - 1 May 2011
Tarr Alexander W, Urbanowicz Richard A, Hamed Mohamed R, Albecka Anna, McClure C Patrick, Brown Richard J P, Irving William L, Dubuisson Jean, Ball Jonathan K
Abstract excerpt
Neutralizing antibodies have a role in controlling hepatitis C virus (HCV) infection. A successful vaccine will need to elicit potently neutralizing antibodies that are capable of preventing the infection of genetically diverse viral isolates. However, the specificity of the neutralizing antibody...
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