Article
Characterization of linear epitope specificity of antibodies potentially contributing to spontaneous clearance of hepatitis C virus.
PloS one - 1 Jan 2021
Ahsan Asma, Dar Saira, Hassan Fareeha, Ghafoor Farkhanda, Yousuf Muhammad Haroon, Shahzad-Ul-Hussan Syed
Abstract excerpt
BACKGROUND: Around 30% of the HCV infected patients can spontaneously clear the virus. Cumulative evidence suggests the role of neutralizing antibodies in such spontaneous resolution. Understanding the epitope specificity of such antibodies will inform the rational vaccine design as such information is limited to date. In addition to conformational epitope targeted antibodies, linear epitope specific antibodies...
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