Article
Broad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV Infection.
Journal of virology - 1 May 2016
Swann Rachael E, Cowton Vanessa M, Robinson Mark W, Cole Sarah J, Barclay Stephen T, Mills Peter R, Thomson Emma C, McLauchlan John, Patel Arvind H
Abstract excerpt
UNLABELLED: During hepatitis C virus (HCV) infection, broadly neutralizing antibody (bNAb) responses targeting E1E2 envelope glycoproteins are generated in many individuals. It is unclear if these antibodies play a protective or a pathogenic role during chronic infection. In this study, we investigated whether bNAb responses in individuals with chronic infection were associated with differences in clinical...
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