Article
Glutathione peroxidase, superoxide dismutase and catalase genotypes and activities and the progression of chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2011
Crawford Amanda, Fassett Robert G, Coombes Jeff S, Kunde Dale A, Ahuja Kiran D K, Robertson Iain K, Ball Madeleine J, Geraghty Dominic P
Abstract excerpt
BACKGROUND: Oxidative stress has been linked to the progression of disease, including chronic kidney disease (CKD). The aim of the present study was to determine the association between single-nucleotide polymorphisms (SNPs) of the antioxidant enzymes, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase and their activities and the progression of CKD. METHODS: This is a prospective cohort study...
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