Article
Relationship between antioxidant enzyme genotype and activity and kidney function: a case-control study.
Clinical nephrology - 1 Aug 2012
Crawford Amanda, Fassett Robert G, Coombes Jeff S, Kunde Dale A, Ahuja Kiran D K, Robertson Iain K, Ball Madeleine J, Geraghty Dominic P
Abstract excerpt
BACKGROUND: Oxidative stress is associated with the progression of chronic kidney disease (CKD). Links between antioxidant enzyme SNPs such as superoxide dismutase (SOD) Ala16Val, glutathione peroxidase (GPx) Pro197Leu and catalase C- 262T and CKD have not been investigated. This study compared antioxidant genotypes and activities of CKD patients with population controls, and determined their relationship to...
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