Article
NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure.
Journal of the American Society of Nephrology : JASN - 1 Jan 2007
Perianayagam Mary C, Liangos Orfeas, Kolyada Alexey Y, Wald Ron, MacKinnon Robert W, Li Lijun, Rao Madhumati, Balakrishnan Vaidyanathapuram S, Bonventre Joseph V, Pereira Brian J, Jaber Bertrand L
Abstract excerpt
Reactive oxygen species are important mediators of injury in acute renal failure (ARF). Although polymorphisms that affect key pro- and antioxidant enzymes might alter the susceptibility to oxidative stress-mediated injury, the use of genetic epidemiology for the study of oxidative stress-related genes has received little attention in ARF. The relationship of single-nucleotide polymorphisms in the coding region...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
