Article
Tumour suppressor gene TP53 mutations in atypical vascular lesions of breast skin following radiotherapy.
Histopathology - 1 Feb 2011
Santi Raffaella, Cetica Valentina, Franchi Alessandro, Pepi Monica, Cesinaro Anna M, Miracco Clelia, Paglierani Milena, De Giorgi Vincenzo, Delfino Chiara, Difonzo Elisa M, Pimpinelli Nicola, Bianchi Simonetta, Sardi Iacopo, Santucci Marco, Massi Daniela
Abstract excerpt
AIMS: Atypical vascular lesions (AVL) occurring at the site of radiotherapy represent an uncommon but well-documented complication in the setting of breast-conserving therapy for breast carcinoma. Although the biological behaviour of AVL has been regarded as benign, it has been suggested that AVL may represent a precursor of angiosarcoma. A better understanding of the biology of AVL is essential in order to...
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