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Article

Ultraviolet-induced p53 mutations in atypical fibroxanthoma.

The American journal of pathology - 1 Jul 1994

Dei Tos A P, Maestro R, Doglioni C, Gasparotto D, Boiocchi M, Laurino L, Fletcher C D

Abstract excerpt

Atypical fibroxanthoma (AFX) is an uncommon neoplasm of the superficial soft tissue occurring in actinically damaged skin of elderly patients. Sun-exposed skin also represents the main site of squamous and basal cell carcinomas and malignant melanoma, and a key role for ultraviolet (UV) radiation in their pathogenesis has long been suspected. UV-related mutations of the p53 gene have been identified in human skin...

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Identifiers

PMID: 8030743
PMCID: PMC1887293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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