Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients.

Breast cancer research and treatment - 1 Jun 2006

Tan Xiang-Lin, Popanda Odilia, Ambrosone Christine B, Kropp Silke, Helmbold Irmgard, von Fournier Dietrich, Haase Wulf, Sautter-Bihl Marie Luise, Wenz Frederik, Schmezer Peter, Chang-Claude Jenny

Abstract excerpt

p53 and p21 play an important role in G1/S checkpoint control in response to ionizing radiation. Yet the genetic polymorphisms in these genes have not been investigated with respect to radiation toxicity in patients. We therefore assessed the association between TP53 Arg72Pro, p53PIN3 and p21 Ser31Arg polymorphisms and the risk of acute skin toxicity after radiotherapy in a prospective study of 446 female breast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p21

Share to Proline

Share to Proportional Hazards Models

Share to Radiotherapy

Share to Serine

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 16331344
DOI: 10.1007/s10549-005-9119-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients.PMID 16331344Read ↗

Association between polymorphisms in the DNA repair genes, XRCC1, APE1, and XPD and acute side effects of radiotherapy in breast cancer patients.Semantic proximity Read ↗

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer.Semantic proximity Read ↗

Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery.Semantic proximity Read ↗

The p53 codon 72 polymorphism, sunburns, and risk of skin cancer in US Caucasian women.Semantic proximity Read ↗

Genetic risk score and acute skin toxicity after breast radiation therapy.Semantic proximity Read ↗

Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of articledeveloping erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery.Semantic proximity Read ↗

Genetic predictors of acute toxicities related to radiation therapy following lumpectomy for breast cancer: a case-series study.Semantic proximity Read ↗

Evaluation of single nucleotide polymorphisms (SNPs) in the p53 binding protein 1 (TP53BP1) gene in breast cancer patients treated with breast-conserving surgery and whole-breast irradiation (BCS + RT).Semantic proximity Read ↗

p53 codon 72 Pro homozygosity increases the risk of cutaneous melanoma in individuals with dark skin complexion and among noncarriers of melanocortin 1 receptor red hair variants.Semantic proximity Read ↗

TP53 Arg72Pro polymorphism and skin cancer risk: a meta-analysis.Semantic proximity Read ↗

Arg72Pro polymorphism of TP53 gene and the risk of skin cancer: a meta-analysis.Semantic proximity Read ↗

Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.