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Article

Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

The Journal of allergy and clinical immunology - 1 Apr 2011

Holt Richard J, Zhang Youming, Binia Aristea, Dixon Anna L, Vandiedonck Claire, Cookson William O, Knight Julian C, Moffatt Miriam F

Abstract excerpt

BACKGROUND: Asthma is a common, chronic inflammatory airway disease of major public health importance with multiple genetic determinants. Previously, we found by positional cloning that PHD finger protein 11 (PHF11) on chromosome 13q14 modifies serum immunoglobulin E (IgE) concentrations and asthma susceptibility. No coding variants in PHF11 were identified. OBJECTIVE: Here we investigate the 3 single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Transcription, Genetic

Source

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Identifiers

PMID: 21320718
DOI: 10.1016/j.jaci.2010.12.015
PMCID: PMC3955022

Genes

PHF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).PMID 21320718Read ↗

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