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Article

Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis.

Genes and immunity - 1 May 2005

Jang N, Stewart G, Jones G

Abstract excerpt

Atopic dermatitis is an increasingly common and debilitating childhood disorder that is often accompanied by asthma and allergic rhinitis. Although the pathology of these disorders is distinct, the majority of cases are atopic, typified by elevated serum IgE. A new locus at chromosome 13q14 centred on the genes SETDB2 and PHF11 and associated with increased total serum IgE has recently been identified. Although...

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Share to Chromosomes, Human, Pair 13
Share to Dermatitis, Atopic
Share to Dermatology and Skin Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 15674390
DOI: 10.1038/sj.gene.6364169

Genes

PHF11
SETDB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis.PMID 15674390Read ↗

Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma.Semantic proximity Read ↗

A functional AT/G polymorphism in the 5'-untranslated region of SETDB2 in the IgE locus on human chromosome 13q14.Semantic proximity Read ↗

Functional characterization of the atopy-associated gene PHF11.Semantic proximity Read ↗

The PHF11 gene is not associated with asthma or asthma phenotypes in two independent populations.Semantic proximity Read ↗

DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selectionSemantic proximity Read ↗

Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population.Semantic proximity Read ↗

Familial pityriasis rubra pilaris is caused by mutations in CARD14.Semantic proximity Read ↗

A common variant on chromosome 11q13 is associated with atopic dermatitis.Semantic proximity Read ↗

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Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumabSemantic proximity Read ↗

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