Article
HLX1 gene variants influence the development of childhood asthma.
The Journal of allergy and clinical immunology - 1 Jan 2009
Suttner Kathrin, Ruoss Isabell, Rosenstiel Philip, Depner Martin, Pinto Leonardo A, Schedel Michaela, Adamski Jerzy, Illig Thomas, Schreiber Stefan, von Mutius Erika, Kabesch Michael
Abstract excerpt
BACKGROUND: Major transcription factors controlling T(H)1 and T(H)2 development, such as T-box transcription factor and GATA3, might be centrally involved in asthma and atopic diseases. Only recently, the homeobox transcription factor H.20-like homeobox 1 (HLX1), interacting closely with T-box tr...
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