Article
The PHF11 gene is not associated with asthma or asthma phenotypes in two independent populations.
Thorax - 1 Jul 2009
McClenaghan J, Warrington N M, Jamrozik E F, Hui J, Beilby J P, Hansen J, de Klerk N H, James A L, Musk A W, Palmer L J
Abstract excerpt
BACKGROUND: Numerous areas of the human genome have previously been associated with asthma and asthma-related phenotypes, but few positive findings have been successfully replicated in independent populations. Initial studies have reported strong associations of variants in the plant homeodomain zinc finger protein 11 (PHF11) gene with serum IgE levels, asthma, airway hyper-responsiveness and childhood atopic...
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