Article
The role of the phoPQ operon in the pathogenesis of the fully virulent CO92 strain of Yersinia pestis and the IP32953 strain of Yersinia pseudotuberculosis.
Microbial pathogenesis - 1 Jun 2011
Bozue Joel, Mou Sherry, Moody Krishna L, Cote Christopher K, Trevino Sylvia, Fritz David, Worsham Patricia
Abstract excerpt
At the genomic level, Yersinia pestis and Yersinia pseudotuberculosis are nearly identical but cause very different diseases. Y. pestis is the etiologic agent of plague; whereas Y. pseudotuberculosis causes a gastrointestinal infection primarily after the consumption of contaminated food. In many gram-negative pathogenic bacteria, PhoP is part of a two-component global regulatory system in which PhoQ serves as...
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