Article
Influence of PhoP and intra-species variations on virulence of Yersinia pseudotuberculosis during the natural oral infection route.
PloS one - 1 Jan 2014
Pisano Fabio, Heine Wiebke, Rosenheinrich Maik, Schweer Janina, Nuss Aaron M, Dersch Petra
Abstract excerpt
The two-component regulatory system PhoP/PhoQ has been shown to (i) control expression of virulence-associated traits, (ii) confer survival and growth within macrophages and (iii) play a role in Yersinia infections. However, the influence of PhoP on virulence varied greatly between different murine models of infection and its role in natural oral infections with frequently used representative isolates of Y....
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