Article
The response regulator PhoP of Yersinia pseudotuberculosis is important for replication in macrophages and for virulence.
Infection and immunity - 1 Sept 2004
Grabenstein Jens P, Marceau Michael, Pujol Céline, Simonet Michel, Bliska James B
Abstract excerpt
Yersinia pestis and Yersinia pseudotuberculosis are closely related facultative intracellular pathogens. The response regulator PhoP was previously shown to be important for Y. pestis survival in macrophages and for virulence in a murine bubonic plague infection assay. Here the importance of PhoP for Y. pseudotuberculosis pathogenesis was investigated. Y. pseudotuberculosis phoP mutants were unable to replicate...
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