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Article

Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague.

Infection and immunity - 1 Apr 2008

Sha Jian, Agar Stacy L, Baze Wallace B, Olano Juan P, Fadl Amin A, Erova Tatiana E, Wang Shaofei, Foltz Sheri M, Suarez Giovanni, Motin Vladimir L, Chauhan Sadhana, Klimpel Gary R, Peterson Johnny W, Chopra Ashok K

Abstract excerpt

Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. We identified a homolog of the Salmonella enterica serovar Typhimurium lipoprotein (lpp) gene in Yersinia species and prepared lpp gene deletion mutants of Y. pseudotuberculosis YPIII, Y. pestis KIM/D27 (pigmentation locus minus), and Y. pestis CO92 with reduced virulence. Mice injected via the...

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Identifiers

PMID: 18227160
DOI: 10.1128/IAI.01529-07
PMCID: PMC2292872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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