Article
Candida albicans Zcf37, a zinc finger protein, is required for stabilization of the white state.
FEBS letters - 9 Mar 2011
Wang Huafeng, Song Wenji, Huang Guanghua, Zhou Zhou, Ding Yufeng, Chen Jiangye
Abstract excerpt
Candida albicans, the most prevalent human fungal pathogen, can switch stochastically between white and opaque phases. In this study, we identified Zcf37, a zinc finger protein, as a new regulator of white-opaque switching. Deletion of ZCF37 increased white-to-opaque switching frequency and stabilized the opaque state. Overexpression of ZCF37 promoted conversion of opaque cells to white phase, but needed...
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