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Article

Interactive expressions of HtrA1 and VEGF in human vitreous humors and fetal RPE cells.

Investigative ophthalmology & visual science - 1 Jun 2011

Ng Tsz Kin, Yam Gary H F, Chen Wei Qi, Lee Vincent Y W, Chen Haoyu, Chen Li Jia, Choy Kwong Wai, Yang Zhenglin, Pang Chi Pui

Abstract excerpt

PURPOSE: High-temperature requirement factor A1 (HtrA1) is associated with exudative age-related macular degeneration, an angiogenic retinal disease related to vascular endothelial growth factor (VEGF). This study investigates the interactive relationship between the expressions of HtrA1 and VEGF. METHODS; The vitreous humor levels of HtrA1, VEGF, and pigment epithelium-derived factor were determined in 55...

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Source

Identifiers

PMID: 21310902
DOI: 10.1167/iovs.10-6773

Genes

RPE
HTRA1
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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