Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Activating Transcription Factor 4 in Murine Choroidal Neovascularization Model

18 Aug 2021

Abstract excerpt

Neovascular age-related macular degeneration (nAMD) featuring choroidal neovascularization (CNV) is the principal cause of irreversible blindness in elderly people in the world. Integrated stress response (ISR) is one of the intracellular signals to be adapted to various stress conditions including endoplasmic reticulum (ER) stress. ISR signaling results in the upregulation of activating transcription factor 4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34445595
DOI: 10.3390/ijms22168890

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Activating Transcription Factor 4 in Murine Choroidal Neovascularization ModelPMID 34445595Read ↗

Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degenerationSemantic proximity Read ↗

Modulation of angiogenesis by genetic manipulation of ATF4 in mouse model of oxygen-induced retinopathy [corrected].Semantic proximity Read ↗

Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degenerationSemantic proximity Read ↗

Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular DegenerationSemantic proximity Read ↗

Neurodegeneration: Keeping ATF4 on a Tight LeashSemantic proximity Read ↗

The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspectiveSemantic proximity Read ↗

MicroRNA-34a suppresses KLF2 to promote pathological angiogenesis through the CXCR4/CXCL12 pathway in age-related macular degenerationSemantic proximity Read ↗

GENE EXPRESSION WITHIN A HUMAN CHOROIDAL NEOVASCULAR MEMBRANE USING SPATIAL TRANSCRIPTOMICSSemantic proximity Read ↗

Regulatory role of HIF-1α in the pathogenesis of age-related macular degeneration (AMD)Semantic proximity Read ↗

Central Role of Oxidative Stress in Age-Related Macular Degeneration: Evidence from a Review of the Molecular Mechanisms and Animal ModelsSemantic proximity Read ↗

Atypical p38 Kinase Signaling in Retinal Vascular Damage and RecoverySemantic proximity Read ↗

Transcriptional Comparison of Human and Murine Retinal NeovascularizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.