Article
HTRA1 promoter polymorphism and risk of age-related macular degeneration: a meta-analysis.
Annals of epidemiology - 1 Oct 2009
Tang Na-Ping, Zhou Bo, Wang Bin, Yu Rong-Bin
Abstract excerpt
PURPOSE: To clarify the role of human high-temperature requirement A-1 (HTRA1) gene promoter polymorphism (-512G>A) in age-related macular degeneration (AMD). METHODS: Relevant studies were identified by searching PubMed and EMBASE database. A logistic regression analysis proposed for molecular association studies was carried out to estimate the genetic effect and the possible genetic model of action. RESULTS:...
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