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Article

Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma

1 Sept 2010

Abstract excerpt

AIMS AND BACKGROUND: Transcriptional silencing induced by hypermethylation of CpG islands in the promoter regions of genes is believed to be an important mechanism of carcinogenesis in human cancers including gastric cancer. A number of reports on methylation of various genes in gastric cancer have been published, but most of these studies focused on cancer tissues or only a single gene. In this study, we...

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PMID: 21302620
DOI: 10.1177/030089161009600515

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