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Article

Clinical significance of DAPK promoter hypermethylation in lung cancer: a meta-analysis

1 Mar 2015

Abstract excerpt

Death-associated protein kinase 1 (DAPK) is an important serine/threonine kinase involved in various cellular processes, including apoptosis, autophagy, and inflammation. DAPK expression and activity are deregulated in a variety of diseases including cancer. Methylation of the DAPK gene is common in many types of cancer and can lead to loss of DAPK expression. However, the association between DAPK promoter...

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PMID: 25848215
DOI: 10.2147/dddt.s78012

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