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Article

NDRG4 hypermethylation is a potential biomarker for diagnosis and prognosis of gastric cancer in Chinese population.

Oncotarget - 31 Jan 2017

Chen Xiaoying, Yang Yong, Liu Jing, Li Bin, Xu Yan, Li Cong, Xu Qi, Liu Guili, Chen Yingmin, Ying Jieer, Duan Shiwei

Abstract excerpt

In order to assess whether N-Myc downstream regulated gene 4 (NDRG4) methylation was associated with the diagnosis and prognosis of gastric cancer, we measured the methylation of NDRG4 promoter and gene body regions among 110 gastric cancer patients using quantitative methods (MethyLight and pyrosequencing). Both NDRG4 promoter and gene body methylation levels were increased in tumor tissues than paired adjacent...

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Identifiers

PMID: 28042954
DOI: 10.18632/oncotarget.14099
PMCID: PMC5352386

Genes

NDRG4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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